Associate Professor of Biomedical Engineering, Director of CV T.E.C. Lab, Director of Marquette University Visualization Lab, and Director of Graduate Studies
Engineering Hall 311
Translational, Experimental and Computational Cardiovascular Research (CV T.E.C.) Lab
Marquette University Visualization Lab
- Quantifying altered blood flow indices as predictors of morbidity after treatments for congenital heart disease
- Correlating altered blood flow indices with the severity of restenosis after stent implantation
- Designing novel engineering devices and interventions for the treatment of cardiovascular diseases, particularly in children
- Developing tools for predictive surgical or transcatheter treatment planning
- Immersive virtual reality approaches to visualization of computational fluid dynamics results and science, technology, engineering and math (STEM) education
Postdoctoral Scholar, 2004-06, Pediatric Cardiology, Stanford University
Ph.D., 2004, Biomedical Engineering, Marquette University
M.S., 2001, Biomedical Engineering, Marquette University
B.S., 2000, Biomedical Engineering, Marquette University
Selected recent publications
C. Chiastra, W. Wu, B. Dickerhoff, A. Aleiou, H. Otake, F. Migliavacca, J.F. LaDisa, Jr.,"Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: from OCT and CT imaging to structural and hemodynamics analyses," J Biomech. 2015 Nov 27. pii: S0021-9290(15)00666-1. doi: 10.1016/j.jbiomech.2015.11.024. [Epub ahead of print]
L. Ellwein, D.S. Marks, R.Q. Migrino, W.D. Foley, S. Sherman, J.F. LaDisa, Jr., "Image-based quantification of 3-D morphology for bifurcations in the left coronary artery: application to stent design," Cathet. Cardiovasc. Intervent.. doi: 10.1002/ccd.26247 [Epub ahead of print]
H. Wang, J.R. Kersten, J.M. Toth, D. Weihrauch, S. Schrepfer, J.F. LaDisa, Jr., "Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats," Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1130-40.
J.F. LaDisa, Jr., S. Bozdag, J. Olson, R. Ramchandran, J.R. Kersten, T.J. Eddinger, "Gene expression in experimental aortic coarctation and repair: candidate genes for therapeutic intervention?," PLoS One. 2015 Jul 24;10(7):e0133356.
M.M. Samyn, R.J. Dholakia, H. Wang, J. Co-Vu, K. Yan, M.E. Widlansky, J.F. LaDisa, Jr., P. Simpson, R. Alemzadeh, "Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes," Pediatr Cardiol. 2015 Apr;36(4):851-61.
LaDisa, John F (Principal), Eddinger, Thomas J (Co-Investigator), Dickerhoff, Benjamin (Supporting), "Mechanistic analysis of mechanical alterations to improve therapeutic interventions for aortic coarctation," Sponsored by American Heart Association, (7/1/2015 - 6/30/2017).
LaDisa, John F (Team Leader), "Partnerships for Excellence through Advanced Visualization," 2015 Strategic Innovation Fund, Marquette University (7/1/2015 - 6/30/2016).
LaDisa, John F (Principal), Hughey, Josh (Other), Ellwein, Laura M (Supporting), "Optical coherence and computed tomography for evaluation of wall shear stress and thrombus potential in coronary arteries after stenting," Sponsored by Kobe University School of Medicine. (August 27, 2012 - December 31, 2015).