John LaDisa, Jr., Ph.D.

John LaDisa

Associate Professor of Biomedical Engineering, Director of CV T.E.C. Lab, Director of Marquette University Visualization Lab
Engineering Hall 311
(414) 288-6739
Email Dr. LaDisa
Complete CV
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Translational, Experimental and Computational Cardiovascular Research (CV T.E.C.) Lab
Marquette University Visualization Lab

Research interests

  • Quantifying altered blood flow indices as predictors of morbidity after treatments for congenital heart disease
  • Correlating altered blood flow indices with the severity of restenosis after stent implantation
  • Designing novel engineering devices and interventions for the treatment of cardiovascular diseases, particularly in children
  • Developing tools for predictive surgical or transcatheter treatment planning
  • Immersive virtual reality approaches to visualization of computational fluid dynamics results and science, technology, engineering and math (STEM) education

Professional preparation

Postdoctoral Scholar, 2004-06, Pediatric Cardiology, Stanford University
Ph.D., 2004, Biomedical Engineering, Marquette University
M.S., 2001, Biomedical Engineering, Marquette University
B.S., 2000, Biomedical Engineering, Marquette University

Selected recent publications

H.S. Kandail, S.D. Trivedi, A.C. Shaikh, T.K. Bajwa, D.P. O’Hair, A. Jahangir, J.F. LaDisa, Jr. “Impact of annular and supra-annular CoreValve deployment locations on aortic and coronary artery hemodynamics.” J Mech Behav Biomed Mater, Oct; 86:131-142, 2018

D.C. Wendell, I. Friehs, M.M. Samyn, L.M Harmann, J.F. LaDisa, Jr. “Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation.” J Surg Res., 218:194-201, 2017

M.M. Samyn, J.F. LaDisa, Jr. “Novel Applications of Cardiovascular Magnetic Resonance Imaging-Based Computational Fluid Dynamics Modeling in Pediatric Cardiovascular and Congenital Heart Disease.” In Magentic Resonance Imaging. 2016 Editor: Christakis Constantinides, InTech

L. Ellwein, M.M. Samyn, M. Danduran, S. Schindler-Ivens, S. Liebham, J.F. LaDisa, Jr. “Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise.” Biomech Model Mechanobiol. 2017 Feb;16(1):75-96. pdf data

D.C. Wendell, M.M. Samyn, J.R. Cava, M.M. Krolikowski, J.F. LaDisa, Jr. “The impact of cardiac motion on aortic valve flow used in computational simulations of the thoracic aorta.” J Biomech Eng. 2016 Sep 1;138(9). doi: 10.1115/1.4033964. pdf

Recent Grants

LaDisa, John F (Co-Investigator), P. Goday (Principal), “Immersive virtual reality caregiver training in pediatrics feeding disorders,” Sponsored by Medical College of Wisconsin Digestive Disease Center (5/1/18-4/30/19)

LaDisa, John F (Co-Principal), C. Bergom (Co-Principal), “Pilot study for the development and implementation of a virtual reality-based breast cancer patient radiation education and anxiety mitigation program,” Sponsored by Medical College of Wisconsin Cancer Center (5/1/18-4/30/19)

LaDisa, John F (Principal), “Mechanisms of morbidity after correcting aortic coarctations of varying severity,” Sponsored by NIH (7/1/18-4/30/22)

LaDisa, John F (Co-Investigator), P. Frommelt (Principal), “Role of cardiac MRI and computational models for post-operative risk stratification in children with intramural anomalous aortic origin of coronary arteries (AAOCA),”Sponsored by Little Hearts for Life (1/01/18-12/31/18)

LaDisa, John F (Principal), Eddinger, Thomas J (Co-Investigator), Dickerhoff, Benjamin (Supporting), "Mechanistic analysis of mechanical alterations to improve therapeutic interventions for aortic coarctation," Sponsored by American Heart Association, (7/1/2015 - 6/30/2017).

LaDisa, John F (Team Leader), "Partnerships for Excellence through Advanced Visualization," 2015 Strategic Innovation Fund, Marquette University (7/1/2015 - 6/30/2016).

LaDisa, John F (Principal), Hughey, Josh (Other), Ellwein, Laura M (Supporting), "Optical coherence and computed tomography for evaluation of wall shear stress and thrombus potential in coronary arteries after stenting," Sponsored by Kobe University School of Medicine. (August 27, 2012 - December 31, 2015).