Multimodal Brain Imaging

Noninvasive neuroimaging modalities such as functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and functional near infrared spectroscopy (fNIRS) provide different levels of spatial and temporal resolution to characterize the brain networks that mediate perception, sensorimotor control and their disruptions by disease. Multimodal neuroimaging approaches offer an avenue to obtain both high spatial and temporal resolution information about brain function but require a better understanding of how direct and indirect measures of neural activity are coupled. The Integrated Neural Systems Laboratory is developing techniques to fully fuse fMRI, EEG, and fNIRS data sets in space and time to investigate the brain networks that mediate perception and action. 

  • Students Discussing Brain Imaging in INSL 
  • Close-up of Brain Imaging + Software Controls

Students discussing recently captured images of the brain

Closeup of Brain Imaging


Selected Publications

*Wagner J., *Zinos A., Chen W-L., Conant L., Malloy M., Heffernan J., Quirk B., Sugar J., Prost R., Whelan J. B., Beardsley S. A., Whelan H. T., (2021), "Comparison of Whole-Head Functional Near-Infrared Spectroscopy with Functional Magnetic Resonance Imaging and Potential Application in Pediatric Neurology," Pediatr. Neurol., 122, p. 68–75. doi: 10.1016/j.pediatrneurol.2021.06.003. PMID: 34301451.

Heugel N., Liebenthal, E., Beardsley S. A., (2019), "Method for spatial overlap estimation of electroencephalography and functional magnetic resonance imaging responses," J. Neurosci. Methods, 328, p. 1–10. DOI: 10.1016/j.jneumeth.2019.108401.


Mangalathu J., Liebenthal, E., Beardsley S. A., (2018), "Optimizing within-subject experimental designs for jICA of multi-channel ERP and fMRI," Front. Neurosci., 12:13, p.1–15. DOI: 10.3389/fnins.2018.00013, PMCID: PMC5787094


*Mangalathu-Arumana J., Beardsley S. A., Liebenthal, E., (2012), "Within-subject joint independent component analysis of simultaneous fMRI / ERP in an auditory oddball paradigm," NeuroImage, 60(4): 2247–57. DOI: 10.1016/j.neuroimage.2012.02.030. PMCID: PMC3321114.



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