The Computational Systems Biology Laboratory at the Marquette University and Medical College of Wisconsin Department of Biomedical Engineering receives ongoing support from the Medical College of Wisconsin, as well as additional support on a per-project basis from organizations such as the National Institutes of Health (NIH) and Advancing a Healthier Wisconsin (AHW).
Dash, Ranjan K. (Principal Investigator); Terhune, Scott (Co-Principal Investigator); Zamora, Anthony (Co-Principal Investigator). "Data-Driven Computational Modeling of Cellular Response in CART Therapy." Sponsored by the Advancing a Healthier Wisconsin Endowment (January 2024–December 2024).
Dash, Ranjan K. (Co-Principal Investigator); "Advanced Ion Channel Modeling and Computational Tool with Application to Voltage-Dependent Anion Channel and Mitochondrial Model Development.” Sponsored by the National Science Foundation (July 1, 2022–June 30, 2025); Co-Principal Investigator—Dexuan Xie, Mathematical Sciences, University of Wisconsin, Milwaukee.
Dash, Ranjan K. (Co-Principal Investigator); "Experimental and computational analysis of mechanisms of mitochondrial-cellular ROS crosstalk in the kidney in salt-sensitive hypertension." MPI R01; Sponsored by NIH/NHLBI (January 1, 2021–November 30, 2024); Co-Principal Investigator/Program Director—Allen W. Cowley, Physiology, MCW.
Dash, Ranjan K. (Co-Principal Investigator); “Predictive Modeling of Cytomegalovirus Replication and Antiviral Efficacy”; MPI R21; Sponsored by NIH/NIAID (March 18, 2020–February 28, 2023); Co-Principal Investigator—Scott Terhune, Microbiology and Immunology, MCW.
Dash, Ranjan K. (Co-Principal Investigator); “Analyzing the Cardiac Power Grid: Adaptive Responses to Fluctuating Local Demand”; MPI U01; Sponsored by NIH/NHLBI (September 15, 2015—May 31, 2021); Co-Principal Investigator/Program Director—James Bassingthwaighte, UW Seattle, WA.
Dash, Ranjan K. (Principal Investigator of Project III); “Project III: Modeling of Mitochondrial and Cellular Function in Anesthetic Cardioprotection”; “PPG: Mechanisms of Anesthetic Cardioprotection”; Sponsored by NIH/NIGMS (March 1, 2015–February 29, 2021); Principal Investigator/Program Director of PPG—Zeljko Bosnjak, Medicine, MCW.
Dash, Ranjan K. (Co-Principal Investigator); “Predictive Computational Modeling to Define Antiviral Efficacy”; Sponsored by Research and Education Program (REP) of Advancing Healthier Wisconsin (AHW) Endowment (February 1, 2017–January 31, 2019); Co-Principal Investigator—Scott Terhune, Microbiology and Immunology, MCW.
Dash, Ranjan K. (Co-Principal Investigator); “Systems Biology Based Tools for Modeling Platelet Storage Lesion for Optimal Blood Transfusions”; Sponsored by CFD Research Corporation-US Army (DOD) SBIR Phase II Project (September 26, 2016–January 25, 2019); Principal Investigator/Project Director—Andrzej Przekwas, CFD Research Corporation, Huntsville, AL.
Dash, Ranjan K. (Principal Investigator/Project Director); “Cations and ROS in Modulating Mitochondrial Function in Normal and Ischemic Hearts”; MPI R01; Sponsored by NIH/NHLBI (April 1, 2010–March 31, 2015); Co-Principal Investigator—Amadou Camara, Anesthesiology, MCW.
Dash, Ranjan K. (Co-Principal Investigator); “Database-Enabled Tools for Regulatory Metabolic Networks”; Sponsored by NSF Biological Database and Informatics (August 1, 2009–July 31, 2012); Principal Investigator/Project Director—Meral Özsoyoglu, CWRU, Cleveland, OH.
Dash, Ranjan K. (Principal Investigator/Project Director); “Computational Modeling of Mitochondrial Energetics”; SDG Sponsored by AHA National Affiliate (July 1, 2007–June 30, 2011).
The Computational Systems Biology Laboratory is looking for researchers with an interest in metabolic systems and computational modeling. For further information on becoming the next addition to the CSBL, contact Dr. Ranjan Dash.
