The Fan Flow Integrated Research Laboratory focuses on developing multi-scale and multi-physics subject-specific computational models that are informed by experimental/clinical data to elucidate the underlying mechanisms of diseases in cardiovascular and brain, and help design/optimize treatments. The Lab also performs ex-vivo beating heart experiments to elucidate the complex mechanisms in relevant biological systems.

Current Projects

 
 

Animation of activation patterns in F2IRL CRT response researchRoles of ischemia and mechanical dys-synchrony in optimizing CRT responses

The F2IRL's CRT response research includes translational findings that can serve as a foundation for future development CRT pacing locations. 

Learn more about CRT Response Research

 

Interventricular displacement mapInterventricular Interactions in heart with implant of left ventricular assist device

The F2IRL seeks to provide insights into interventricular interactions for Left Ventricular Assist Device recipients.

Learn more about Interventricular Interaction Research

 

Animation of myocardial demand supplyMyocardial demand supply under physiological and pathological conditions

Research findings from the F2IRL's Myocardial Demand project will facilitate CRT pacing location optimization, improving responder rate. 

Learn more about Myocardial Demand Supply Research

 

Image of brain seen from the posterior view, intersected by sagittal planeExperimental studies and computational modeling on brain tissues

The F2IRL seeks to develop a computational modeling framework elucidating the constitutive behavior of brain tissue. 

Learn more about Computational Modeling for Brain Tissues

 

F2IRL Funding

Research in the Fan Flow Integrated Research Laboratory is supported by Marquette University, the Medical College of Wisconsin, and the American Heart Association.