CaRE Facilities

The Cardiovascular Regenerative Engineering Laboratory has facilities located on campuses of both Marquette University and the Medical College of Wisconsin.  These facilities are equipped with a variety of resources intended to support investigators in the creation and assessment of engineered tissue constructs.  

 

Featured Capabilities 

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Chemical Synthesis Station

Chemical Synthesis Station in the Cardiovascular regenerative Engineering LaboratoryThe Chemical Synthesis Station is used to synthesize nanoparticles—including superparamagnetic iron oxide nanoparticles (SPION)—for magnetic cell targeting applications.

 

 

 

Electrospinning Station 

Electrospinning station in the Cardiovascular Regenerative Engineering LaboratoryThe Electrospinning Station is used to fabricate polymer biomaterials from sub-micron and nanoscale fibers.  These biomaterials are useful in cardiovascular regenerative engineering applications.

 

 

 

Heart Valve Hydrodynamic Performanace Test Station

Heart Valve Assessment Platform in the Cardiovascular Regenerative Engineering LaboratoryThe Heart Valve Hydrodynamic Performance Test Station is used to assess the hydrodynamic performance of prototype heart valves to ISO 5840 standards.  It is capable of applying physiological flows and pressures and measuring effective orifice area and regurgitant fraction.

 

Vascular Graft Test Station

Vascular Graft Testing Station in the Cardiovascular Regenerative Engineering LaboratoryThe Vascular Graft Test Station is used to assess the mechanical properties of prototype vascular grafts to ISO 7198 standards.  It is capable of applying physiological and super-physiological pressures and measuring dynamic radial compliance and burst strength.

 

 

 

 

 

 

 

 

 

 

 

Mechanical Test Station

Mechanical Testing Station in the Cardiovascular Regenerative Engineering LaboratoryThe Mechanical Test Station is used to assess the mechanical properties of biomaterials and tissues.  It is capable of dynamic mechanical analysis, tensile testing, and compressive testing.

 

 

 

 

Parallel Plate Flow Chambers

Parallel Plate Flow Chambers in the Cardiovascular Regnerative Engineering LaboratoryParallel Plate Flow Chambers are used to expose cells to precise values of steady or pulsatile fluid shear stress.

 

 

 

Cell Culture Facility

Cell Culture Room in the Cardiovascular Regenerative Engineering LaboratoryThe Cell Culture Facility is used to culture cells using aseptic technique.

 

 

 

 

3D Bioprinter

3D Bioprinter in the Cardiovascular Regenerative Engineering LaboratoryThe 3D Bioprinter is used to fabricate three-dimensional constructs consisting of a biomaterial scaffold and one or more cell types in a precise geometric pattern.

 

 

 

 

 

 

 

 

Chemical Workroom

Chemical Workroom in the Cardiovascular Regenerative Engineering LaboratoryThe Chemical Workroom is used to store and handle hazardous chemicals.

 

 

 

 

Fluorescence and Light Microscopy

Microscope Room at the Cardiovascular Regenerative Engineering LaboratoryFluorescence and light microscopy are used to image cells and tissues, typically following a labeling procedure to highlight the structures of interest