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Research at the Cardiovascular Regenerative Engineering Laboratory uses regenerative engineering and nanotechnological techniques to develop living tissue replacements for blood vessels, cardiac valves, and vascular and cardiac patches. Learn more about CaRE's ongoing research below.
Magnetic Endothelialization of Implantable Cardiovascular Devices
The team at CaRE is using nanotechnology to develop magnetic vascular grafts and biosynthetic magnetic heart valves.
Regenerative Engineering Approaches to Treating Cardiovascular Disease
Patients suffering from cardiovascular disease, or CVD, can benefit from cardiovascular tissues that can self-repair and remodel with a patient over time. To help make this possible, CaRE is developing a new method of integrating cells and growth factors with nanofiber biomaterials.
Mechanical Testing Methods for Tissue-engineered Vascular Grafts
In order to be effective, synthetic vascular grafts need to be durable yet flexible, and the reliability of a given testing methodology is paramount in assessing a graft's viability. With this in mind, CaRE is has developed a novel approach to the mechanical testing of synthetic vascular grafts.
Top-down Prosthetic Heart Valve Fabrication
In order to promote the viability of using self-healing, human-tissue-generated heart valves for patients requiring heart valve repair or replacement, CaRE is developing a top-down approach to prosthetic heart valve fabrication.
Establishing Factors Controlling Heart Valve Development
Researchers at the CaRE Lab are looking to create a heart valve that can integrate and grow with its environment. In order to create such a valve, researchers must first further existing knowledge about the development of native heart valves, both healthy and diseased.
Learn more about Factors Controlling Heart Valve Development
Electromagnetically Aligned Nanofiber Biomaterials
Researchers at the CaRE Lab are seeking to improve the biocompatibility and durability of the materials used in prosthetic heart valves. To work towards this goal, CaRE is developing electrospinning processes to produce a material composed of aligned polymer nanofibers with a magnetic core.
Research at the Cardiovascular Regenerative Engineering Laboratory is supported by Marquette University and the Medical College of Wisconsin, with individual grants being awarded on a per-project basis from various institutions, including:
