Airway Lab Research

Research Projects | Investigative Approaches | Funding

Research at the Airway Biomechanics Laboratory at the Marquette University and Medical College of Wisconsin Department of Biomedical Engineering employs a diverse investigative toolset and focuses on improving the diagnosis and treatment of respiratory diseases.  

 

Research Projects

Photograph of human airwayBiomechanics of Upper Airway Collapse in Obstructive Sleep Apnea

With its application of fluid and solid mechanics simulations to the biomechanics of upper airway collapse in OSA, the Airway Lab seeks to improve our understanding of OSA pathophysiology and develop virtual surgery planning tools to optimize the outcomes of surgical intervention.

 Learn more about Upper Airway Collapse in OSA

 

3D Rendering of upper airwayVirtual Surgery Planning for Nasal Airway Obstruction

The Airway Lab is developing virtual surgery planning methods to optimize surgical outcomes for nasal airway obstruction.

 Learn more about Virtual Surgery Planning for Nasal Airway Obstruction

 

 

Anatomy of upper airwayRespiratory Drug Delivery

The Airway Lab applies computational fluid dynamics (CFD) to quantify the regional doses of aerosol medications such as nasal sprays and dry powder inhalers delivered to different parts of the respiratory tract.  

 Learn more about Respiratory Drug Delivery

 

 

 

Endoscopy of esophagusQuantitative Endoscopy

The Airway Lab is developing methods to quantify the cross-sectional area of the airway (e.g., nasal cavity, pharynx, trachea) from endoscopy videos.

Learn more about Quantitative Endoscopy

 

 

 

Illustration of computational model discussing airway surface liquid volumeRegulation of Airway Surface Liquid Volume in Cystic Fibrosis Epithelia

The Airway Lab is working to develop a mathematical model of ASL volume and pH regulation for use in the interpretation of electrophysiology experiments and the development of pharmaceutical therapies.

 Learn more about Regulation of Airway Surface Liquid Volume

 

Investigative Approaches

The Airway Biomechanics Laboratory uses a wide range of computational techniques, in vitro experiments, and in vivo measurements to investigate respiratory biomechanics

 

About Investigative Approaches

 

Funding

Research at the Airway Biomechanics Laboratory receives ongoing support from the Medical College of Wisconsin and additional support on a per-project basis from various institutions and endowments.

 

Learn more about Funding