For more information on the Respiratory Biomechanics Laboratory, contact Dr. Guilherme Garcia.
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The Airway Biomechanics Laboratory is composed of an experimental lab and a computational lab. In addition, researchers have access to institutional resources provided by MCW's Engineering Laboratory and Research Computing Center. Together, these state-of-the-art resources ensure investigators are well-equipped to perform cutting-edge research in airway biomechanics.
The experimental laboratory space consists of approximately 65 square feet of benchtop space. The laboratory is well equipped for pressure-flow measurements in replicas of the human upper airway.
FlowmetersHans Rudolph pneumotach series 4700, TSI mass flowmeter model 4045
Pressure cathetersMillar Mikro-Cath pressure catheter
Pressure transducersOmega model #PX409-015GUSBH
Pressure sensorsValidyne DP45-26-A-1-S-4-D Pressure Sensor
House vacuumHouse vacuum of approximately negative 25” of Hg
Cyclic pumpsHarvard Apparatus large-animal ventilator with tidal volume of 0–750 ml and pump frequency of 0–50 cycles/minute
Laser line scannerMicro-Epsilon scanCONTROL 2600-100
The Computational Lab is composed of four high-performance, 12-core workstations appropriately equipped with software for fluid mechanics and solid mechanics simulations and engineering analysis.
Mimics is the industry standard software for medical-image analysis and anatomy engineering. In the Airway Biomechanics Laboratory, Mimics is used to reconstruct anatomical models from computed tomography (CT) scans and magnetic resonance images (MRI).
ANSYS is a software package designed for finite element analysis (FEA), computational fluid dynamics (CFD) simulations, and fluid-structure interaction (FSI) simulations. The package used in the Airway Lab includes ANSYS SpaceClaim, ANSYS ICEM CFD, ANSYS Mechanical APDL, ANSYS Fluent, ANSYS System Coupling, ANSYS CFD-Post, and ANSYS Workbench.
Fieldview is a software for post-processing CFD simulations.
Matlab is a computing environment for data and image analysis. In the Airway Biomechanics Laboratory, Matlab is used for a wide range of applications, including to solve the differential equations of our mathematical model of airway surface liquid volume regulation.
In addition to the resources listed above, investigators in the Airway Biomechanics Laboratory enjoy access to MCW's Research Computing Center, as well as the 3D Systems ProJet 3500 HDMax 3D Printer located in MCW's Engineering Laboratory.
Research Computing Center
The Research Computing Center at MCW provides access to a 552 Core Linux MPI cluster, four Graphical Processing Unit Servers with Three Nvidia K40 (2880 cores) each, four Graphical Processing Unit Servers with Four Nvidia K80 (4992 cores) each, and a MATLAB Distributed Computing Cluster with 256 workers.
3D System ProJet 3500 HDMax 3D Printer
The 3D Systems ProJet 3500 HDMax 3D Printer located in MCW's Engineering Laboratory has a resolution of 0.025 to 0.050 mm per 25.4 mm linear dimension. The printing material is the VisiJet M3-X print media, which results in ABS-like hard plastic.