Dr. Ranjan Dash

Dr. Ranjan DashMarquette University

Medical College of Wisconsin, Biomedical Engineering C-2910

MilwaukeeWI53201United States of America(414) 955-4497rdash@mcw.edu

Professor, Co-Director of Graduate Studies

Joint Department of Biomedical Engineering

Professor

MCW Department of Physiology

Director

Computational Systems Biology Laboratory (CSBL)

Learn more about CSBL

Detailed Publications & Profiles

Professional Preparation

• Postdoc, 2006, Computational Systems Biology, Case Western Reserve University, Cleveland
• Postdoc, 2003, Computational Systems Biology, University of Washington, Seattle
• Postdoc, 2000, Computational Biofluid Dynamics, Texas A&M University, College Station
• Ph.D., 1998, Computational Biofluid Dynamics, Indian Institute of Technology, Delhi, India
• M.Sc., 1991, Applied Mathematics, Utkal University, Bhubaneswar, Orissa, India

Courses Taught

BIEN 6931 Special Topics in BME—Modeling and Simulations of Integrated Cellular Systems

VIEW BIEN COURSE CATALOGUE

Research Interests

• Computational Systems Biology & Bioengineering
• Mitochondrial, Cellular & Cardiovascular Physiology
• Cellular/Mitochondrial Metabolism & Redox Biology

Specific Research Interests

• Pulmonary and systemic microcirculatory gas exchange and acid-base regulation

• Physiologically-based pharmacokinetic modeling of drug transport and metabolism

• Integrated blood-tissue solute transport and cellular/mitochondrial metabolism

• Modeling and analysis of large-scale biochemical networks, protein-protein interaction networks, signaling network, and gene regulatory networks

• Cellular/mitochondrial calcium and reactive oxygen species homeostasis and signaling

• Cardiac electrophysiology, calcium handling, and excitation-contraction coupling

• Cardiac substrate and energy metabolism, oxidative stress, and ischemia-reperfusion injury

• Renal substrate and energy metabolism, oxidative stress, and salt-sensitive hypertension

Recent Publications

View recent publications uploaded from the Faculty Collaboration Database.

Honors and Awards

Sep 2025: Excellent in Mentorship Award, Medical College of Wisconsin

Dec 2020:   Dean’s Choice Outstanding Graduate School Educator Award for the academic year 2019–2020 for commitment to excellence in graduate education, Graduate School of Biomedical Sciences, Medical College of Wisconsin

Jul 2018:   Award of Tenure for distinction in scholarly and intellectual achievements, Joint Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin

Dec 2017:   Dean’s Choice Outstanding Graduate School Educator Award for the academic year 2016–2017 for commitment to excellence in graduate education, Graduate School of Biomedical Sciences, Medical College of Wisconsin

Aug 2015:   Outstanding Faculty Service Award for service to the Library Committee (July 2014–June 2015), Medical College of Wisconsin

Sep 2011:   Founding Faculty, Virtual Physiological Rat Center (an NIH-funded National Center for Systems Biology) and Center for Computational Medicine, Medical College of Wisconsin.

Dec 2010:   Marquis Who’s Who in Science and Engineering for the year 2011–2012 for noteworthy achievements that are of significant value to the society

Recent Grants

• Dash, Ranjan (Co-Principal Investigator); Cowley, Allen (Principal Investigator); “High Salt Remodels Renal Cortical and Proximal Tubular Metabolism: Metabolic Fuels, Oxidative Stress, and Hypertension.” Sponsored by the NIH: National Heart Lung and Blood Institute (January 2025–December 2028).
• Dash, Ranjan K. (Principal Investigator); Terhune, Scott (Co-Investigator); “Modeling Human Cell Cycle Dysregulation in Cancer for Drug Discovery.” Sponsored by the Advancing a Healthier Wisconsin Endowment (January 2025–December 2025).
• Dash, Ranjan K. (Principal Investigator); Terhune, Scott (Co-Investigator); Zamora, Anthony (Co-Investigator); "Data-Driven Computational Modeling of Cellular Response in CART Therapy." Sponsored by the Advancing a Healthier Wisconsin Endowment (January 2024–December 2024).
• Dash, Ranjan K. (Principal Investigator); Terhune, Scott (Co-Principal Investigator); Zamora, Anthony (Co-Principal Investigator). "Data-Driven Computational Modeling of Cellular Response in CART Therapy." Sponsored by the Advancing a Healthier Wisconsin Endowment (January 2024–December 2024).
• Dash, Ranjan K. (Co-Principal Investigator); Xie, Dexuan (Co-Principal Investigator, UWM). "Advanced Ion Channel Modeling and Computational Tool with Application to Voltage-Dependent Anion Channel and Mitochondrial Model Development." Sponsored by the National Science Foundation (July 1, 2022–June 30, 2025).
• Dash, Ranjan K. (Co-Principal Investigator); Cowley, Allen (Co-Principal Investigator). "Experimental and computational analysis of mechanisms of mitochondrial-cellular ROS crosstalk in the kidney in salt-sensitive hypertension."; Sponsored by the National Heart, Lung and Blood Institute (NHBLI) of the National Institutes of Health (January 1, 2021–November 30, 2024).