Biomedical Imaging

The Biomedical Imaging research groups in the Marquette Medical College of Wisconsin Joint Department of Biomedical Engineering focus on developing new techniques to noninvasively visualize the structure and function of living systems for clinical analysis and medical intervention. Below, learn more about the many BME laboratories contributing to the development of novel imaging technologies and other advancements in this field.

 

Biomedical Imaging Laboratories

 

Lens from Ocular Imaging Technology employed by the Advanced Ocular Imaging ProgramAdvanced Ocular Imaging Program

Dr. Joseph Carroll and researchers in the Advanced Ocular Imaging Program (AOIP) use non-invasive imaging techniques—such as optical coherence tomography and adaptive optics scanning light ophthalmoscopy—to examine both the structure and function of the living eye.  The AOIP collaborates with researchers around the world to advance the application of these and other ocular imaging tools to a range of retinal and systemic diseases. 

Learn more about the AOIP | Learn more about Dr. Carroll

 

 

Biophotonics Sensor developed in the Biophotonics LaboratoryBiophotonics Laboratory

The Biophotonics Laboratory develops optical imaging, spectroscopy, and sensing techniques for non- or minimally invasive detection and treatment of cancers and other conditions. Current projects include deep-ultraviolet fluorescence scanning microscopy for intraoperative assessment of breast tumor margins, smartphone microendoscopy for cervical cancer screening, laser ablation of liver tumors with real-time monitoring, optical confirmation and monitoring of endotracheal tube position, and photo-biomodulation or low-level laser therapy.

Learn more about the Biophotonics Lab | Learn more about Dr. Yu

 

 

Isolated rodent lung on ventilation-perfusion machineComputational Lung Physiology Laboratory

The Computational Lung Physiology Laboratory (CLPL) uses Micro-CT technology and nuclear medicine to develop experimental and computational strategies to investigate lung physiology at all levels—from molecular, to cellular, to whole-organ and body.  The goal is to identify mechanisms and processes involved in lung diseases and injuries such as sepsis and acute respiratory distress syndrome (ARDS).  The CLPL then develops treatments for these diseases that target the elucidated mechanisms.  

Learn more about the CLPL | Learn more about Dr. Audi

 

 

Animation of activation patterns in F2IRL CRT response researchFan Flow Integrated Research Laboratory

Dr. Lei Fan and members of the Fan Flow Integrated Research Laboratory (F2IRL) use experimental imaging techniques in their efforts to better understand the electrophysiological mechanics of cardiac function, particularly in the case of demand-supply mismatch and lead placement after pacemaker implantation. 

Learn more about the F2IRL  |  Learn more about Dr. Fan

 

MRI scans of the brainFunctional MRI Research Laboratory

Led by Dr. Kristina Ropella, the Functional MRI Research Laboratory specializes in the use of MRI to assess brain function (fMRI).  Researchers in the Functional MRI Research Laboratory create imaging strategies, sequences, and instrumentation related to fMRI.  This specialization may include neuroscience and vision research.  

Learn more about Dr. Ropella

 

 

Virtual reality hardware with computer screen showing human walkingIntegrative Neural Systems Laboratory

The Integrative Neural Systems Laboratory is developing techniques to fully fuse data sets from functional magnetic resonance imaging (fMRI), electroencephalography (EEG), and functional near infrared spectroscopy (fNIRS) in space and time to investigate the brain networks that mediate perception and action. 

Learn more about the INSL | Learn more about Dr. Beardsley

 

 

Projection of anatomy of human thorax on VisLab Cave wallMarquette Visualization Laboratory

The Marquette Visualization Lab (VisLab) demonstrates how visualization technology can be used in learning, research, and industry.  Collaborating with researchers from many disciplines, VisLab visualizes scientific data, clinical environments, and meta-data in ways that can stimulate new ideas.  Marquette's Visualization Lab includes a 3D-immersion cave and content development lounge where researchers can work on developing and programming new visualization tools.

Learn more about VisLab

 

 

Example of imaging produced in Medical Imaging Systems LabMedical Imaging Systems Laboratory

The Medical Imaging Systems Laboratory (MISL) focuses on the design and optimization of medical imaging systems and algorithms.  Current projects are investigating Spectral CT, photon-counting CT, and software algorithms for rapid, patient-specific radiation dose estimation.  MISL engages both academic and industrial partners to improve image quality, decrease patient radiation dosing, and uncover new diagnostic capabilities in medical imaging systems.

Learn more about MISL

 

 

NanoparticlesNanomedicine & Image-Guided Interventions Laboratory

The interests of the Nanomedicine and Image-Guided Interventions Laboratory (NIGIL) include molecular imaging in small animal models, gold nanoparticles with tunable surface plasmons for imaging and photo-thermal ablation, cancer imaging and therapy, near-infrared and shortwave infrared optical imaging and tomography systems, and multimodal optical and MRI contrast agent development.

Learn more about NIGILLearn more about Dr. Joshi

 

 

Nine renderings of human brainNeuroimaging Research Laboratories

Led by Drs. Schmit, Scheidt and Beardsley, the Neuroimaging Research Laboratories include the Integrative Neural Engineering & Rehabilitation Laboratory (INERL), the Neuromotor Control Laboratory (NMCL), and  the Integrative Neural Systems Laboratory. Together, these laboratories focus on neural systems and neurorehabilitation imaging, including areas in MRI such as diffusion tensor imaging (DTI) and tractography, and multi-modal fusion of fMRI, magnetoencephalography (MEG) and electroencephalography (EEG).  

Learn more about INERL  |  Learn more the NMCL  |  Learn more about Dr. Beardsley

 

 

Image of cones and rods of retina with gradient overlayOcular & Computer Vision Laboratory

The Ocular & Computer Vision Laboratory (OCVL)  uses non-invasive imaging techniques such as adaptive optics ophthalmoscopy, optical coherence tomography, and fundus photography combined with computer vision techniques to assess the structure and function of the living retina at both a macro and sub-micron scales. The OCVL actively collaborates with clinical, academic, and industrial partners to augment the development of experimental and computational tools and further understanding of vision and ocular pathologies.

Learn more about the OCVL  |  Learn more about Dr. Cooper

 

 

Human brain rendered using neuroimaing technology used in SNAP LabSensory Neuroscience, Attention, & Perception Laboratory

To understand how human behavior is guided by perception, the SNAP Lab uses neuroimaging and neural stimulation methods to study the neurobiology of attention and perception in the visual, auditory, and olfactory domains. In addition, the SNAP Lab develops computational tools used to analyze data acquired using functional Magnetic Resonance Imaging (fMRI), Diffusion Imaging (DTI/DSI), and Transcranial Magnetic Stimulation (TMS).

Learn more about the SNAP Lab  |  Learn more about Dr. Greenberg

  

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