Dr. Robert F. Cooper

Headshot of Dr. Robert F. Cooper
Dr. Robert F. CooperMarquette University

Cramer Annex, 160C

MilwaukeeWI53201United States of America
(414) 288-5205Google Scholar

Assistant Professor

Joint Department of Biomedical Engineering

Assistant Professor

MCW Department of Ophthalmology and Visual Sciences


Ocular & Computer Vision Laboratory (OCVL)


Learn more about OCVL



Advanced Ocular Imaging Program (AOIP)


Learn more about AOIP


Professional Preparation

  • Postdoctoral Fellowship, 2015–2019, University of Pennsylvania
  • Ph.D., 2016, Biomedical Engineering, Marquette University
  • B.S., 2009, Biomedical Engineering, Marquette University

Courses Taught

BIEN 3200 Computer Applications in Biomedical EngineeringDesign and implementation of computer techniques for the acquisition and analysis of biomedical data and the modeling of physiologic phenomena

BIEN 3310 Control Systems for Biomedical Engineering—An introduction to the principles of control systems theory for biomedical engineers

BIEN 4280 Biocomputers Design Lab 1—Software design and validation, microprocessors, computer architecture, real-time computing, embedded software, graphical user interface and networking

BIEN 4290 Biocomputers Design Lab 2Continuation of BIEN 4280 with emphasis on high performance computing in workstation environments

BIEN 4510/5510 Image Processing for the Biomedical Sciences—An introduction to biomedical image processing with an emphasis on applications in diagnostic medicine, biology and biomedical research

BIEN 4931/5931/6931 Topics in Biomedical Engineering—Advanced Biomedical Image Processing




Research Interests

  • Measuring photoreceptor mosaic structure and function using advanced noninvasive techniques
  • Development of image processing and automated analysis tools
  • Clinical imaging for studying the etiology of retinal disease

Recent Publications

View recent publications uploaded from the Faculty Collaboration Database.


  • Cooper, RF (Principal Investigator); “Non-Invasive Functional Assessments for Translational Retinal Therapeutics.” Sponsored by the National Institutes of Health (8/01/2023–7/31/2026). Major Goal: To develop a precise tree shrew imaging technique for single-cell functional assessment and versatile small animal imaging tools, with the ultimate aim of facilitating the translation of novel preclinical therapies to humans.
  • Carroll, J. (Principal Investigator); Cooper, RF (Co-PI); “Retinal Contributions to Vision Loss in Albinism.” Sponsored by the National Institutes of Health—National Eye Institute (07/01/2022–06/01/2026). Major Goal: To examine the influence of retinal melanin on visual acuity and the phenotypic spectrum of foveal morphology, characterize disruptions in foveal post-receptoral circuitry in subjects with albinism, and map rod photoreceptor mosaic topography in subjects with albinism.
  • Cooper, RF (Principal Investigator); “Assessing the Function of Individual Cells in Patients with Inherited Retinal Degenerative Disease.” Sponsored by the Foundation Fighting Blindness (06/30/202006/29/2023). Major goal: To enhance and explore the functional signal from individual cells in patients with degenerative diseases.
  • Buckland E. (Co-Principal Investigator), Carroll J. (Co-Principal Investigator), Cooper RF (Co-Investigator); “Validating Automated Photoreceptor Analytics Software for Degenerative Eye Disease Research and Biopharma Clinical Trials.”  Sponsored by National Institutes of Health—National Eye Institute (03/01/2020–02/28/2022).  Major goal: To extend the functionality of MOSAIC as a commercial-ready, efficient and user-friendly photoreceptor analysis software for quantifying AO images.
  • Connor (Principal Investigator), Cooper RF (Co-Principal Investigator); “Assessing Function at a Cellular Scale in Patients with Inherited Retinal Degenerations.” Traditional Pilot Award sponsored by the Clinical and Translational Science Institute of Southeast Wisconsin (08/01/2020–07/31/2021). Major goal: To translate a nascent cellular-scale functional assay to a clinical environment.


"Non-invasive Assessment of Human Cone Photoreceptor Function" Awarded by the United States Patent Office on March 21, 2023, to The Trustees of the University of Pennsylvania.  Contributors include Drs. Robert Cooper, Jessica I.W. Morgan (University of Pennsylvania), David H. Brainard (University of Pennsylvania), and William S. Tuten (UC Berkeley).

Investigator working in the lab.

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