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Dr. Brandon Tefft, Assistant Professor of Biomedical Engineering at Marquette University and the Medical College of Wisconsin, who specializes in the application of regenerative engineering and nanotechnology techniques for development of living tissue replacements for cardiovascular structures, has recently been selected as a guest editor of a special issue of Bioengineering discussing cell-ECM interactions for tissue engineering and regeneration.
It is increasingly appreciated that the extracellular matrix (ECM) provides not only structural support, but also dynamic signaling cues that influence cellular behavior. In the context of tissue engineering and tissue regeneration, the ECM plays a critical role in many aspects, including the regulation of cell survival, cellular reorganization, contractility, as well as in the regulation of engineered cardiovascular tissue formation and function. This issue explores cellular interactions with naturally derived ECMs, biomimetic materials, and synthetic hydrogels. For example, the ECMs can take the form of 3D porous scaffolds, bio-inks for 3D bioprinting, or decellularized ECMs. We invite manuscripts that focus on how cell–ECM interactions lead to advances in tissue engineering or in vivo tissue regeneration, as well as in the improved understanding of the underlying molecular biology.
Dr. Ngan F. Huang
Dr. Brandon J. Tefft
Bioengineering is an international, scientific, peer-reviewed, open-access journal on the science and technology of bioengineering. Published monthly by MDPI, Bioengineering is indexed with Scopus, SCIE, PubMed, PMC, CAPlus/SciFinder, Inspec, and additional publications.